Congenital central hypoventilation syndrome

نویسنده

  • Shuk-Kuen CHAU
چکیده

Congenital central hypoventilation syndrome (CCHS) is a rare disorder of the automatic control of breathing. The literary misnomer "Ondine's curse" has been used in prior literatures and the disease was first described in 1970 by Mellins et al.1 The hallmark of the disease is alveolar hypoventilation with insensitivity to hypoxaemia and hypercapnia, most pronounced during sleep, but the clinical spectrum of severity can be wide. For many years, the underlying cause for this disease was a mystery and the disease was mostly diagnosed based on exclusion of other causes of central hypoventilation.

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تاریخ انتشار 2013